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Sixteen words carry P second and R third, and one of them opens in a way almost nothing else in English does.
MPRET was the title of the ruler of Albania, and it opens with MP. Almost no English word begins that way, which makes it worth recognising even though you would never guess it.
The rest of the page is conventional. S opens eleven of the sixteen and every one of those runs SPR, a cluster English is perfectly comfortable with.
SPRAY, APRON, SPREE and SPRIG are the entries in general use. SPRAT and SPRIT are recognisable, and APRES turns up in apres ski.
E and A each take it in four of the sixteen, with I and U on three each and O on two. Nothing dominates, so the letter after the R rarely settles anything.
T and G each close three of the sixteen, which is unusual for a group this small. SPRIT, SPRAT, SPRIG and SPRAG all finish that way.
APRON is the one entry both common and outside the S branch, which makes it the most informative guess here.
APRON tests the A, O and N, none of which the SPR branch uses much. It also settles whether the word starts with S, which is the biggest question here.
A prop used in mining, or a bar to stop a wheel turning. SPROD, a young salmon, sits nearby and is equally specialist.
Taken with, or smitten by, borrowed from French. It appears in older literary English.
A sprit is a spar supporting a sail and a sprat is a small fish. They differ in the fourth box and have nothing in common.