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Just two words carry S second and W third, and both are built the same way.
ASWAY means swaying and ASWIM means afloat or swimming. Each is a short verb with an A fastened to the front, which is how English makes adverbs of state like AFOOT and AFIRE.
Neither has been in ordinary use for a long time. They survive in verse and in word lists, where the A prefix construction stayed productive long after everyday English stopped using it.
A is the only opening letter and the fourth and last boxes take one letter each per word. There is no distribution here to read at all.
Floating, or immersed in liquid. A room aswim with water is flooded.
Almost never. You would meet it in nineteenth century poetry and very little else.
The A prefix comes from an older preposition meaning on or in. It gave us abed, afoot, ablaze and asleep, and the pattern froze rather than dying out.
ASWIM, since its meaning is guessable from the verb inside it. ASWAY is the rarer of an already rare pair.
There is not. Zero of the two carry one.