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Only nine words hold Y second and O third, and most of them come from Greek medicine.
MYOMA is a tumour of muscle tissue, MYOID means resembling muscle, and MYOPE, MYOPS and MYOPY all relate to short sightedness. M opens five of the nine, more than every other letter combined.
Greek myo means muscle and ops means eye, and between them they account for almost this entire page. It is a group built out of two word roots rather than out of English.
HYOID, MYOID and PYOID all end the same way, and the suffix means resembling or shaped like. A hyoid bone is shaped like the Greek letter upsilon, and pyoid means resembling pus.
AYONT means beyond, in Scots, and RYOTS are Indian peasant farmers. Neither has any connection to the Greek medical vocabulary that fills the rest of the page.
D closes three of the nine, which is the OID ending showing through, and I and P each take three of the fourth box.
No entry here is everyday English. If a puzzle lands on this pattern it is drawing on specialist vocabulary, and reading the list is faster than reasoning.
A small U shaped bone in the neck that supports the tongue. It is the only bone in the human body that touches no other bone.
A myope is a short sighted person and MYOPS is a variant of the same word. MYOPY is the condition itself.
Beyond or on the far side of, in Scots. Ayont the hill means over the hill.
A peasant farmer or tenant cultivator in India. The word comes from Arabic through Urdu and appears throughout colonial era writing.