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Twelve words carry S second and S third, and only three of them are words you would use.
All three are common English and any of them could reasonably be the answer. Everything else here is a borrowing, an abbreviation or a term you would need to look up.
ASSAY is a chemical test and ASSAI an Italian musical direction meaning very. ISSEI names a first generation Japanese emigrant and OSSIA marks an alternative passage in a score.
ASSOC is a straight abbreviation of association and ASSOT an archaic verb meaning to befool. The ground gets thin fast past the first three entries.
A takes seven of the twelve, with E and I on two each and O taking the last. No consonant will sit in front of a doubled S at this length.
The fourth box is almost as tight. A and E each take four of the twelve, which covers most of the group before you reach the final letter.
ISSUE repeats the S and its U sits where few other entries put one. ASSET tests the T and covers more of what the rest of the page uses.
Very, in Italian musical directions, as in allegro assai. It is unrelated to the acai berry despite the resemblance.
A marking in sheet music introducing an alternative version of a passage, usually an easier one.
A Japanese person who emigrated to North America, the first generation. Nisei and sansei follow for the generations after.
The pattern puts S in the second and third boxes, so the repeat is forced by the page rather than chosen by the words.