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Fifty four words put T first and N third, and the vowels divide the second box almost evenly between them.
E takes the second box in thirteen of the fifty four, O in twelve, A in eleven, I in nine and U in seven. Y adds two more and no consonant appears there at all.
With fifty four words behind that spread, no single guess in the second box cuts much. It does tell you the answer is a vowel, which rules out most first instincts.
TENSE, TONAL, TANGO, TINGE and TUNED come from different vowels and differ from each other in several boxes. Guessing across them covers far more ground than the same number of words from any one branch.
TANGS, TINGS, TONGS and TUNGS differ in one box. TONED, TUNED and TINED do the same, as do TONER, TUNER and TENOR. Nearly every stem here takes the same handful of tails, which is why the page narrows so slowly.
S closes fourteen of the fifty four, twenty six percent. E leads the fourth box on twelve words with G on ten, and only six words repeat a letter.
TENSE or TONAL. Both are common, both avoid the plural ending, and they test two different vowels at once.
Both appear on this list. A tonne is a metric ton and tenne is a heraldic colour, and they differ only in the second box.
Fourteen of the fifty four do, because every vowel branch takes a plural. Ruling one out is the biggest single cut this page offers.