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Only nine words start with IC, and two of them are in general use.
I takes the third box in three of the nine, with K and T on two each and H and O on one apiece. Five letters appear there in total.
ICONS and ICING are the two entries most people would produce. ICIER and ICILY follow and both are reachable if you think of the comparative forms.
ICHOR is the fluid said to run in the veins of the gods, and it turns up in crosswords more than in conversation. ICKER is an ear of corn and ICKLE is a childish form of little.
ICTIC and ICTUS are the remaining pair, both relating to a stress or beat in verse or medicine. Neither is a word you would reach for.
R closes three of the nine, thirty three percent, more than any other letter, with S on two. Nothing here repeats a letter, so a visible double rules the page out entirely.
Both are ordinary words and they differ in every box after the IC. ICING is the more common of the two in writing.
The fluid said to flow in the veins of the gods. It is a crossword staple rather than everyday vocabulary.
IC is common at the end of English words and rare at the start. Nine entries is everything the language offers at five letters.