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129 five letter words begin with RO, and the third box holds no clear favourite at all.
A second O leads at about twelve percent, U at eleven and T at ten. W takes eight, then B and M at five each.
ROOMS, ROUND, ROYAL, ROUTE and ROADS are the most common entries, and they reach five different third letters.
ROSES, ROLES, ROBOT and ROCKS follow, which makes this a group with plenty of ordinary vocabulary behind the leaders.
ROOMS, ROOTS and ROOST share ROO, while ROUND, ROUTE and ROUGH share ROU. Between them those two carry nearly a quarter of the page.
ROUND is the strongest opener. It covers the second largest shape and its N and D are two of the commonest endings in the group.
If the U misses, ROOMS covers the other big shape without repeating anything ROUND already tested.
ROUND, marginally. It tests five distinct letters while ROOMS repeats its O, and both cover shapes of a similar size.
Not closely. Its Y sits on a branch that holds little else, so it is a reasonable guess only once the O and U shapes have failed.
Only the last box. Both share ROCK, so a guess on either narrows the other to a single question.