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One hundred one words start with DE, and no third letter takes more than a ninth of them.
A takes the third box in twelve of the one hundred one, L in eleven and B in ten. Twenty letters appear there, so the page divides into small pieces rather than branches.
DEATH, DEALS, DEBUT, DECAY and DELAY are the entries most likely to be wanted, with DEBIT, DENSE and DEPTH close behind.
A leads the fourth box on eighteen words, eighteen percent, with E on thirteen. Between them they cover a third of that box.
DEBUG, DEFOG, DEGAS and DEICE are all the prefix attached to a stem, and they share nothing beyond the opening pair.
DEATH, DEPTH and DENSE are ordinary roots where the DE is simply the start of the word. The page mixes both kinds freely.
That mixture is why the third box scatters so widely. There is no single logic behind what follows the DE.
S closes twenty nine of the one hundred one, twenty nine percent, with Y on fourteen and T on ten. DEATH tests the T ending and a common third letter at once.
It is among the strongest. It is common, it tests the A third box and its TH ending appears on few other entries.
DE serves as both a prefix and the start of ordinary roots, so the letters behind it follow no single pattern. Twenty appear in the third box.
Twenty nine, which is twenty nine percent. Ruling out a plural is the biggest single cut this page offers.