Enter criteria and click Find Words
Nine five letter words begin with IO, and more than half of them run IOD.
D takes about fifty six percent of the third box. N, R and T account for one entry each, and that is the whole page.
IONIC and IOTAS are the two entries a player would name. The IOD forms are chemistry spellings for iodine compounds rather than everyday words.
Guess IONIC first. If the N misses, IOTAS is the only other entry outside the chemistry group, so the page resolves in two turns.
They are real chemistry spellings and they sit in the list, but whether a puzzle would use one depends on the word list behind it.
Yes, it uses I in the first and third boxes. That repeat is worth noticing because nothing else here does it.
The plural of iota, the Greek letter, used in English to mean a very small amount. It is the second most usable entry here.