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Only twenty four words place O second and Y third, and English usually puts that pair somewhere else.
BOIL, COIN and JOINT keep the I, while BOY, TOY and ENJOY take the Y. The convention is consistent enough that OY at positions two and three feels wrong even when it is right.
That is why the count here is twenty four while the OI page runs to several times as many. The sound is the same and the spelling convention sends it elsewhere.
Both are entirely ordinary words, both fit the pattern, and they differ in the opening letter alone. Between them they account for most of the traffic this page gets.
E takes the fourth box in seven of the twenty four, A takes six and L takes five. No letter runs away with it.
R closes four of the twenty four and U closes four, which is a strange pairing to find at the end of a group this small.
You cannot from the pattern. Only the first letter separates them, so you need a guess that tests R or L directly.
A large South American rodent, also called a nutria. It is one of the few entries here ending in U.
A liqueur flavoured with fruit kernels. It also ends in U, which is why that letter shows up so often on this page.
The plural of goy, a Hebrew and Yiddish word for a non Jewish person. It is in general English use.