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Only twenty three words carry A second and X third, and T opens seven of them.
TAXES, MAXIM, FAXES, TAXIS and WAXED are the ones in general use. TAXON and TAXUS belong to biology, and the rest are variants you would rarely reach for.
E fills the fourth box in fifteen of the twenty three, sixty five percent. With only five letters appearing there at all, landing on the X tells you most of what comes next.
X is one of the highest scoring tiles in Scrabble and Words With Friends. A short word like TAXES puts it in play without needing a long rack.
TAXES ends in S, which ten of these do, so it rules out more. WAXED tests the D ending instead.
Zero of the twenty three do, so you can rule a repeated letter out from the start.
The botanical name for the yew genus. Most players would never produce it, but it is a valid entry in this group.