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Seventy seven words start with AL, and the third box spreads across more letters than any branch can carry.
A takes the third box in eleven of the seventy seven, with I and O on ten each and L on eight. G adds seven more.
Sixteen letters appear there in total, and the leader holds only fourteen percent. That makes the third box a poor place to aim a first guess.
ALERT, ALIVE, ALIEN, ALIGN and ALARM are the entries a puzzle is most likely to want, with ALBUM, ALIBI and ALLOY behind them.
L takes the third box in eight words and every one of them doubles the L straight away. ALLAY, ALLEY, ALLOT, ALLOW and ALLOY all work that way.
That branch accounts for most of the ten repeats on the page, so a visible double points at it immediately.
S closes fourteen of the seventy seven, eighteen percent, with E on ten and D on eight.
A and E take the fourth box in twenty one between them. So test the last box first, then the fourth, and leave the third alone.
Both are common and they differ in three boxes. ALERT also tests the T ending, which six words here take.
Sixteen letters appear there and the leader takes only eleven words. No guess aimed at that box removes much of the page.
A compound formed in a particular chemical reaction. It is one of several technical entries that fill out the count.