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One hundred twenty one words place L second and O third, and a doubled O runs through a good part of the group.
CLOSE, ALONG, BLOOD, FLOOR and BLOCK are the most common. ALONE, CLOCK, GLOBE, GLORY and CLOUD all come up constantly.
O takes the fourth box in fourteen of the one hundred twenty one, which puts a second O straight after the first. BLOOD, BLOOM, FLOOD, FLOOR, ALOOF, SLOOP and CLOOT all work that way.
C takes twenty six of the one hundred twenty one, F takes nineteen, S takes seventeen and G takes sixteen, with B and P behind. A opens ten more, in ALONE, ALONG, ALOOF and ALOUD.
Past the doubled O the fourth box spreads across twenty three letters, with T on eleven and W on ten. That is one of the widest fourth boxes on the site.
So the doubled O is worth testing early precisely because everything else is so scattered. Rule it out and you face a long tail rather than a second big branch.
CLOSE tests the S and E, which sit in the two busiest last box positions. BLOOD is useful only if you already suspect the doubled O.
Cloth is fabric and a clout is a blow or, in older usage, a piece of rag. They share three letters and split from the fourth.
A strong gust or blast of wind. It is an old word surviving mainly in word lists now.
Eighteen of the one hundred twenty one do, most of them the doubled O. English built a lot of common words on that shape and kept nearly all of them.