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Twenty four words put L first and S third, and the second box is split almost evenly between five letters.
A and Y tie at six words each, U takes five, O takes four and I takes three. Nothing else appears there at all.
Y doing as much work as A is the notable part. LYSED, LYSES, LYSIN, LYSIS, LYSOL and LYSSA all put Y in the second box, which is far more than that letter usually manages.
LASER, LASSO and LASTS carry the A branch. LOSER and LOSES carry O, LUSTY and LUSTS carry U, and LISTS and LISPS carry I.
That is a short list of genuinely common words for a page of twenty four. Most of the Y branch is chemistry and most of the rest is specialised.
E fills the fourth box in nine of the twenty four, thirty eight percent, with S and T on four each behind it.
S closes nine of the twenty four, thirty eight percent, ahead of R and Y on three each. Four words repeat a letter, mostly the doubled S of LASSO, LASSU and LYSSA.
It is the most common word here and it tests the A branch and the E fourth box together, which covers a lot of the page in one turn.
Six words take it, nearly all of them scientific terms built on the lysis root. It is a quirk of this pattern rather than anything general about Y.
A disinfectant, used as a common noun on this list. It sits in the Y branch with LYSIN and LYSIS.